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Rhodiola

ENERGIZE INGREDIENT

Rhodiola

ENERGIZE INGREDIENT

INGREDIENT RESEARCH

Fatigue Fighter

Fatigue Fighter

Endurance

Endurance

Adaptogen

Adaptogen

WHAT SCIENCE SAYS:

Rhodiola has an anti-fatigue effect that increases mental performance and the ability to concentrate

Rhodiola has an anti-fatigue effect that increases mental performance and the ability to concentrate

FUN FACT

The inhospitable elements of high elevation, cold weather, and intense sun are the very conditions that have allow Rhodiola to develop its adaptogenic compounds

The inhospitable elements of high elevation, cold weather, and intense sun are the very conditions that have allow Rhodiola to develop its adaptogenic compounds

Evidence Based Facts

A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue

Erik M Olsson , Bo von Schéele, Alexander G Panossian
Planta Med. 2009 Feb;75(2):105-12. doi: 10.1055/s-0028-1088346.


ABSTRACT:

The aim of the study was to assess the efficacy of the standardised extract SHR-5 of roots of Rhodiola Rosea L. in the treatment of individuals suffering from stress-related fatigue. The phase III clinical trial took the form of a randomised, double-blind, placebo-controlled study with parallel groups. Participants, males and females aged between 20 and 55 years, were selected according to the Swedish National Board of Health and Welfare diagnostic criteria for fatigue syndrome. A total of 60 individuals were randomised into two groups, one ( N = 30) of which received four tablets daily of SHR-5 extract (576 mg extract/day), while a second ( N = 30) received four placebo tablets daily. The effects of the extract with respect to quality of life (SF-36 questionnaire), symptoms of fatigue (Pines' burnout scale), depression (Montgomery -Asberg depression rating scale - MADRS), attention (Conners' computerised continuous performance test II - CCPT II), and saliva cortisol response to awakening were assessed on day 1 and after 28 days of medication. Data were analysed by between-within analyses of variance. No serious side effects that could be attributed to the extract were reported. Significant post-treatment improvements were observed for both groups (placebo effect) in Pines' burnout scale, mental health (SF-36), and MADRS and in several CCPT II indices of attention, namely, omissions, commissions, and Hit RT SE. When the two groups were compared, however, significant effects of the SHR-5 extract in comparison with the placebo were observed in Pines' burnout scale and the CCPT II indices omissions, Hit RT SE, and variability. Pre- VERSUS post-treatment cortisol responses to awakening stress were significantly different in the treatment group compared with the control group. It is concluded that repeated administration of R. ROSEA extract SHR-5 exerts an anti-fatigue effect that increases mental performance, particularly the ability to concentrate, and decreases cortisol response to awakening stress in burnout patients with fatigue syndrome.

* These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

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